SCHEMBL16449846

SCHEMBL16449846

C=CC(=O)OCOc1ccc(C(=O)Oc2ccc(OC(=O)C3CCC(C)CC3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.41
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.35
LMNA P02545 3/20 0.35
MAPK1 P28482 1/20 0.35
THRB P10828 3/20 0.34
HPGD P15428 2/20 0.34
PRSS1 P07477 1/20 0.34
ACR P10323 1/20 0.34
NPC1 O15118 2/20 0.33
F2 P00734 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16449849 1.00 ELANE (0.41) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16449860 0.90 ELANE (0.41) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16557883 0.89 ELANE (0.40) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16451644 0.89 ELANE (0.40) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16449858 0.88 ELANE (0.41) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL15397343 0.87 KMT2A (0.50) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL22580209 0.87 KMT2A (0.50) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL19930181 0.85 NPC1 (0.40) ELANEKMT2ASMN1; SMN2POLBMAPT
SCHEMBL10000377 0.84 SMN1; SMN2 (0.44) ELANEKMT2ASMN1; SMN2HTTTDP1
SCHEMBL16449883 0.84 SMN1; SMN2 (0.44) ELANEKMT2ASMN1; SMN2HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9977163-B2 Orientation layer for optically anisotropic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 US disclosed
US-9696475-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9625629-B2 Process for producing optically anisotropic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-18 US disclosed
US-9606279-B2 Process for producing optically anisotropic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-28 US disclosed
US-9594274-B2 Process for producing optically anisotropic film component SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-14 US disclosed
US-9575232-B2 Method for producing optically anisotropic laminated body SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-21 US disclosed
US-9541691-B2 Optical Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-10 US disclosed
US-9529130-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-27 US disclosed
US-9482801-B2 Method for producing long circular polarization plate and long circular polarization plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-11-01 US disclosed
US-9482802-B2 Method for producing long retardation film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-11-01 US disclosed
US-20150042943-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150042940-A1 METHOD FOR PRODUCING OPTICALLY ANISOTROPIC LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150043071-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150044487-A1 ORIENTED-FILM-FORMING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150042941-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150043073-A1 METHOD FOR PRODUCING LONG CIRCULAR POLARIZATION PLATE AND LONG CIRCULAR POLARIZATION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150041051-A1 LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150043072-A1 METHOD FOR PRODUCING LONG RETARDATION FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150044392-A1 OPTICALLY-ANISOTROPIC-LAYER-FORMING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150042944-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed