SCHEMBL16449883

SCHEMBL16449883

C=CC(=O)OCOc1ccc(OC(=O)[C@H]2CC[C@H](C(=O)Oc3ccc(OC)cc3)CC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ELANE P08246 1/20 0.41
RAB9A P51151 3/20 0.39
THRB P10828 2/20 0.39
NPC1 O15118 2/20 0.39
UBE2N P61088 1/20 0.39
GAA P10253 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
F2 P00734 1/20 0.37
TGM2 P21980 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000377 1.00 SMN1; SMN2 (0.44) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL15397343 0.94 KMT2A (0.50) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL22580209 0.94 KMT2A (0.50) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL10000345 0.90 KMT2A (0.42) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL19422250 0.89 HTT (0.45) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL16450994 0.89 THRB (0.52) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL16449861 0.89 THRB (0.52) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL19759388 0.89 KMT2A (0.39) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL16450991 0.87 HTT (0.41) SMN1; SMN2HTTKMT2ATDP1ELANE
SCHEMBL16449888 0.87 HTT (0.41) SMN1; SMN2HTTKMT2ATDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9977163-B2 Orientation layer for optically anisotropic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-22 US disclosed
US-9696475-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9594274-B2 Process for producing optically anisotropic film component SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-14 US disclosed
US-9575232-B2 Method for producing optically anisotropic laminated body SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-21 US disclosed
US-9541691-B2 Optical Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-10 US disclosed
US-9529130-B2 Optical film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-12-27 US disclosed
US-9383492-B2 Elliptical polarization plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
US-9372296-B2 Optically anisotropic film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-21 US disclosed
US-20160146995-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-26 US disclosed
US-20160062013-A1 ORIENTATION LAYER FOR OPTICALLY ANISOTROPIC FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-03 US disclosed
US-20150070764-A1 METHOD FOR PRODUCING LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-12 US disclosed
US-20150049291-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 US disclosed
US-20150042943-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150042940-A1 METHOD FOR PRODUCING OPTICALLY ANISOTROPIC LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150041051-A1 LAMINATED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150042944-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150044487-A1 ORIENTED-FILM-FORMING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150043071-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150042942-A1 ELLIPTICAL POLARIZATION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed
US-20150044392-A1 OPTICALLY-ANISOTROPIC-LAYER-FORMING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-12 US disclosed