SCHEMBL10000345

SCHEMBL10000345

C=CC(=O)OCOc1ccc(OC(=O)C2CCC(OC)CC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ELANE P08246 2/20 0.39
THRB P10828 3/20 0.37
HPGD P15428 1/20 0.37
F2 P00734 1/20 0.36
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16557883 0.94 ELANE (0.40) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL16451644 0.94 ELANE (0.40) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL15397343 0.91 KMT2A (0.50) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL22580209 0.91 KMT2A (0.50) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL16449883 0.90 SMN1; SMN2 (0.44) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL10000377 0.90 SMN1; SMN2 (0.44) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL26476800 0.87 KMT2A (0.43) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL19422250 0.86 HTT (0.45) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL16449861 0.86 THRB (0.52) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL16450994 0.86 THRB (0.52) KMT2AHTTSMN1; SMN2TDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8094263-B2 Optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-20100053509-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed