4-Nitroaniline

4-Nitroaniline

SCHEMBL16451

Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
KMT2A Q03164 3/20 0.75
MAPT P10636 3/20 0.75
MEN1 O00255 2/20 0.75
ESR1 P03372 2/20 0.62
CYP19A1 P11511 2/20 0.62
ESR2 Q92731 2/20 0.62
PKM P14618 1/20 0.58
ACHE P22303 1/20 0.56
HSD17B10 Q99714 1/20 0.56
LOXL2 Q9Y4K0 1/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA3 P07451 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Nitroaniline SCHEMBL27963818 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
SCHEMBL9065915 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL13529022 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL702809 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL11498181 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL7158091 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL6956705 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL356765 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL21825602 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1
4-Nitroaniline SCHEMBL7158084 0.97 ALDH1A1 (0.95) ALDH1A1KMT2AMAPTMEN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 30257 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120944379-B Preparation method of yellow light absorbing dye for myopia prevention and myopia prevention paper 湖北蓝图纸业有限公司 2026-05-19 CN claimed
US-12629555-B2 Long-term fire retardant with magnesium sulfate and corrosion inhibitors and methods for making and using same PERIMETER SOLUTIONS, LP (US) 2026-05-19 US claimed
CN-122037054-A Polymer, patterning composition, patterning film, patterning method and application thereof 珠海基石科技有限公司 2026-05-15 CN claimed
CN-122036516-A Synthesis process of 4,4' -diaminodiphenylamine 河北科技大学 2026-05-15 CN claimed
CN-122043864-A Patterning composition, patterning film, patterning method and application thereof 珠海基石科技有限公司 2026-05-15 CN claimed
CN-122042355-A Pretreatment and detection method for measuring content of polycyclic aromatic hydrocarbon in biochar-based fertilizer 江苏省农产品质量检验测试中心 2026-05-15 CN claimed
CN-122010953-A Pyrazolo [1, 5-alpha ] pyrimidine compound, and synthetic method and application thereof 豫北医学院 2026-05-12 CN claimed
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
CN-122010890-A Organic fluorescent probe for detecting hypoxia, preparation method and application 内蒙古大学 2026-05-12 CN claimed
CN-118142583-B Method for catalyzing nitro compound hydrogenation by porous polymer-based metal catalyst 浙江大学 2026-05-12 CN claimed
US-4140718-A Preparation of N,N'-dialkylphenylenediamines UOP INC. (US) 1979-02-20 US claimed
US-4119620-A Novel dipeptide derivatives, salts thereof, and method of measuring enzyme activity AJINOMOTO CO., INC. (JP) 1978-10-10 US claimed
US-4114369-A MULTILAYER SHEET OF METAL FOILS, INTUMESCENT MATERIAL AND GLASS CLOTH REINFORCEMENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-09-19 US claimed
US-4101491-A USEFUL AS BINDERS FOR NONWOVEN FIBERS THE B. F. GOODRICH COMPANY (US) 1978-07-18 US claimed
US-4097470-A AMINO ACID, ACRYLATE OR ACRYLAMIDE ADDITION POLYMER CESKOSLOVENSKA AKADEMIE VED (CS) 1978-06-27 US claimed
US-4062865-A Process for the synthesis of substituted indolenines SNAMPROGETTI S.P.A. (IT) 1977-12-13 US claimed
US-4036680-A Delignification of lignocellulosic material with a soda pulping liquor containing a Diels Alder adduct of benzoquinone or naphthoquinone in admixture with a nitro aromatic compound CANADIAN INDUSTRIES, LTD. (CA) 1977-07-19 US claimed
US-4013715-A PROCESS FOR THE MANUFACTURE OF 2-HALO-ETHANE-PHOSPHONIC ACID DIHALIDES AND VINYL-PHOSPHONIC ACID DIHALIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed
US-4009228-A TACKIFIERS FOR RUBBERS AND THERMOPLASTICS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-02-22 US claimed
US-3986931-A γ-GLUTAMYL-4-NITROANILIDE COMPOUNDS AND THEIR USE IN DETERMINING γ-GLUTAMYL TRANSPEPTIDASE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-10-19 US claimed