SCHEMBL16451628

SCHEMBL16451628

CC1=C(O)[C@@H]([C@@H](O)CO)OC1=O

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.68
LMNA P02545 2/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
TYR P14679 2/20 0.43
HSPD1 P10809 1/20 0.43
HSPE1 P61604 1/20 0.43
TST Q16762 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MANBA O00462 1/20 0.37
THRB P10828 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12750421 1.00 MAPT (0.68) MAPTLMNAL3MBTL1TYRHSPD1
SCHEMBL13778159 0.83 LMNA (0.55) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL15577247 0.81 MAPT (0.93) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL28240604 0.81 MAPT (0.93) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL27955458 0.81 MAPT (0.93) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL2564750 0.81 MAPT (1.00) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL11981759 0.81 MAPT (1.00) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL10957988 0.81 MAPT (1.00) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL21114349 0.81 MAPT (1.00) MAPTLMNAL3MBTL1TYRHSPD1
Ascorbic Acid SCHEMBL786 0.81 MAPT (1.00) MAPTLMNAL3MBTL1TYRHSPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9295630-B2 Vitamin C complexes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-03-29 US disclosed
US-20150250169-A1 ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT NIPPON SODA CO., LTD. (JP) 2015-09-10 US disclosed
US-20150045426-A1 VITAMIN C COMPLEXES Universite Paris-Saclay (FR) 2015-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250169-A1 ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT CBR3, OSR1, OXSR1 MAPT 4717/4885LMNA 4569/4885L3MBTL1 2165/4885
US-20150045426-A1 VITAMIN C COMPLEXES PROC, CYP27B1, CYP24A1 MAPT 4482/4885LMNA 894/4885L3MBTL1 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.