SCHEMBL16452771

SCHEMBL16452771

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 1.00
MAPK1 P28482 1/20 1.00
GLRA1 P23415 2/20 0.66
GLRA2 P23416 2/20 0.66
CYP2C9 P11712 1/20 0.66
HSD17B10 Q99714 1/20 0.66
GUSB P08236 1/20 0.66
PTAFR P25105 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13702705 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL30331275 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL500085 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL16653652 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL500086 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL13960092 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL14078020 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL13702832 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL14078047 0.94 KDM4E (0.88) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL13960101 0.93 KDM4E (0.86) KDM4EMAPK1GLRA1GLRA2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9084755-B2 Method for extracting and separating ginkgolides CHENGDU BAIYU TECHNOLOGY PHARMACY CO., LTD. (CN) 2015-07-21 US disclosed
US-9084755-B2 Method for extracting and separating ginkgolides CHENGDU BAIYU TECHNOLOGY PHARMACY CO., LTD. (CN) 2015-07-21 US disclosed
US-20150044311-A1 METHOD FOR EXTRACTING AND SEPARATING GINKGOLIDES CHENGDU BAIYU PHARMACEUTICAL CO., LTD. (CN) 2015-02-12 US disclosed
US-20150044311-A1 METHOD FOR EXTRACTING AND SEPARATING GINKGOLIDES CHENGDU BAIYU PHARMACEUTICAL CO., LTD. (CN) 2015-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150044311-A1 METHOD FOR EXTRACTING AND SEPARATING GINKGOLIDES COG8, CYP8B1, GTPBP10 KDM4E 3380/4885MAPK1 3051/4885GLRA1 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.