SCHEMBL500086

SCHEMBL500086

C[C@@H]1C(=O)O[C@H]2C(O)C34[C@@H]5OC(=O)[C@]3(O[C@@H]3OC(=O)C(O)C34[C@H](C(C)(C)C)[C@H]5O)[C@@]12O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 1.00
MAPK1 P28482 1/20 1.00
GLRA1 P23415 2/20 0.66
GLRA2 P23416 2/20 0.66
CYP2C9 P11712 1/20 0.66
HSD17B10 Q99714 1/20 0.66
GUSB P08236 1/20 0.66
PTAFR P25105 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13702705 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL16452771 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL30331275 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL500085 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL16653652 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL13960092 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL14078020 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL13702832 1.00 KDM4E (1.00) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL14078047 0.94 KDM4E (0.88) KDM4EMAPK1GLRA1GLRA2CYP2C9
SCHEMBL13960101 0.93 KDM4E (0.86) KDM4EMAPK1GLRA1GLRA2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622941-B2 Anticoccidial composition comprising ginkgo leaves and use thereof CJ CHEILJEDANG CORPORATION (KR) 2026-05-12 US claimed
CN-122012537-A Gene GbCYP A6 for promoting synthesis of ginkgolide and application thereof 扬州大学 2026-05-12 CN claimed
EP-3782619-B1 USE OF GINKGO BILOBA TERPENE LACTONE IN PREPARATION OF DRUGS FOR PREVENTION AND/OR TREATMENT OF TREMORS AND HEALTHCARE PRODUCTS CHENGDU BAIYU PHARMACEUTICAL CO LTD (CN) 2026-02-25 EP claimed
US-12545694-B2 Cannabidiol derivatives, preparation method thereof and use thereof CHENGDU BAIYU PHARMACEUTICAL CO., LTD. (CN) 2026-02-10 US claimed
EP-4088723-B1 CANNABIDIOL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF CHENGDU BAIYU PHARMACEUTICAL CO LTD (CN) 2025-08-06 EP claimed
CN-117269404-B Thin-layer chromatography identification method of gingko seed formula particles and stir-fried gingko seed formula particles 四川新绿色药业科技发展有限公司 2025-05-02 CN claimed
CN-119907666-A Application of ginkgolide in preparing medicament for preventing or treating diabetes and diabetic complications 成都百裕制药股份有限公司 2025-04-29 CN claimed
US-12285488-B2 Oral dosage form containing theobromine-free cocoa LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2025-04-29 US claimed
WO-2025073211-A1 METHOD FOR IDENTIFYING GINKGO FORMULA GRANULES AND FRIED GINKGO FORMULA GRANULES BASED ON THIN-LAYER CHROMATOGRAPHY 四川新绿色药业科技发展有限公司 2025-04-10 WO claimed
US-20250082703-A1 GINKGO BILOBA KETONE ESTER CAPSULE AND PREPARATION METHOD THEREOF SPH XING LING SCI. & TECH. PHARMACEUTICAL CO., LTD. (CN) 2025-03-13 US claimed
WO-1999020291-A9 PHARMACEUTICAL GRADE GINKGO BILOBA PHARMAPRINT INC (US) 1999-08-12 WO claimed
WO-1999026643-A1 METHODS OF PREPARATION OF BIOGINKGO PHARMANEX, INC. (US) 1999-06-03 WO claimed
WO-1999020291-A2 PHARMACEUTICAL GRADE GINKGO BILOBA PHARMAPRINT, INC. (US) 1999-04-29 WO claimed
US-5599950-A Preparation process of ginkgolide B from ginkgolide C SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S) (FR) 1997-02-04 US claimed
EP-0680968-A1 Method for the preparation of ginkgolide B from ginkgolide C SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1995-11-08 EP claimed
US-5241084-A PREPARATION PROCESS OF GINKGOLIDE B FROM GINKGOLIDE C SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1993-08-31 US claimed
EP-0532512-A4 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS 1993-05-05 EP claimed
EP-0532512-A1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS. ALLERGAN INC (US) 1993-03-24 EP claimed
WO-1991018608-A1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS ALLERGAN, INC. (US) 1991-12-12 WO claimed
US-4734280-A PLATELET ACTIVATING FACTOR; ANTISHOCK AGENTS, GINKOLIDES SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1988-03-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545694-B2 Cannabidiol derivatives, preparation method thereof and use thereof CNR1, CNR2, OPRM1 KDM4E 4100/4885MAPK1 1016/4885GLRA1 132/4885
US-12622941-B2 Anticoccidial composition comprising ginkgo leaves and use thereof ALPI, SI, SLC10A2 KDM4E 2282/4885MAPK1 3048/4885GLRA1 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.