SCHEMBL1645484

SCHEMBL1645484

Brc1cccc(N(CC2CO2)CC2CO2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
HPGD P15428 1/20 0.33
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
KDM1A O60341 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
HTR7 P34969 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156988 0.87 LMNA (0.45) LMNAMAPTALDH1A1POLBL3MBTL1
SCHEMBL17480430 0.87 LMNA (0.45) LMNAMAPTALDH1A1POLBL3MBTL1
SCHEMBL1645405 0.80 MAPT (0.41) LMNAMAPTALDH1A1POLBL3MBTL1
SCHEMBL29655226 0.79 ALDH1A1 (0.53) LMNAALDH1A1POLBL3MBTL1TP53
SCHEMBL18473404 0.79 HCRTR2 (0.41) LMNAMAPTALDH1A1POLBL3MBTL1
SCHEMBL24282250 0.79 TAAR1 (0.46) LMNAALDH1A1POLBL3MBTL1TP53
SCHEMBL6229306 0.79 LMNA (0.40) LMNAALDH1A1POLBL3MBTL1TP53
SCHEMBL1643625 0.79 MEN1 (0.41) LMNAMAPTALDH1A1POLBL3MBTL1
SCHEMBL14691398 0.78 ALDH1A1 (0.46) LMNAALDH1A1POLBL3MBTL1TP53
SCHEMBL19828100 0.78 LMNA (0.39) LMNAALDH1A1POLBL3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2256163-B1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES (JP) 2018-11-14 EP disclosed
US-20160159993-A1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2016-06-09 US disclosed
US-20110097568-A1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL, AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES, INC 2011-04-28 US disclosed
EP-2256163-A1 EPOXY RESIN COMPOSITION, FIBER-REINFORCED COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME Toray Industries, Inc. (JP) 2010-12-01 EP disclosed