Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.41 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260682 | 0.95 | DUSP5 (0.45) | PTPN1DUSP5DUSP6LCKFYN | |
| SCHEMBL6856353 | 0.95 | PTPN1 (0.42) | PTPN1DUSP5DUSP6LCKFYN | |
| Potassium Ion SCHEMBL2965238 | 0.95 | PTPN1 (0.42) | PTPN1DUSP5DUSP6LCKFYN | |
| SCHEMBL6292110 | 0.95 | PTPN1 (0.42) | PTPN1DUSP5DUSP6LCKFYN | |
| Zinc Ion SCHEMBL2469908 | 0.95 | PTPN1 (0.42) | PTPN1DUSP5DUSP6LCKFYN | |
| SCHEMBL6906244 | 0.95 | PTPN1 (0.42) | PTPN1DUSP5DUSP6LCKFYN | |
| SCHEMBL5009688 | 0.90 | PTPN1 (0.38) | PTPN1DUSP5DUSP6LCKFYN | |
| SCHEMBL9574902 | 0.88 | LCK (0.53) | PTPN1DUSP5DUSP6LCKFYN | |
| SCHEMBL7714612 | 0.84 | LCK (0.48) | PTPN1DUSP5DUSP6LCKFYN | |
| Terephthalic Acid SCHEMBL8053920 | 0.83 | CA2 (0.48) | PTPN1DUSP5DUSP6CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643501-B2 | Oxidizing, ionic and short oil alkyd resins for coatings with excellent balance of hardness and gloss | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-05-09 | — | — | US | claimed |
| CN-112424287-B | Oxidative, ionic and short oil alkyds for coatings with an excellent balance of hardness and gloss | 科思创(荷兰)有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-110272553-A | Adaptability vapor barrier | 罗地亚经营管理公司 | 2019-09-24 | — | — | CN | claimed |
| CN-109485841-A | A kind of continuous polymerization method of the alkali soluble copolymer polyester of not antimony-containing catalyst | 浙江恒澜科技有限公司 | 2019-03-19 | — | — | CN | claimed |
| CN-105143317-B | Aliphatic/semi-aromatic block copolyamides | 罗地亚经营管理公司 | 2018-11-09 | — | — | CN | claimed |
| EP-2448997-B1 | MODIFIED POLYAMIDE COMPOSITION | RHODIA OPERATIONS (FR) | 2018-10-03 | — | — | EP | claimed |
| CN-105431471-A | Polyamides comprising ME-BHT, compositions comprising such a polyamide, shaped articles comprising such a polyamide or such a composition | RHODIA OPERATIONS | 2016-03-23 | — | — | CN | claimed |
| CN-105143317-A | Aliphatic/semi-aromatic block copolyamides | RHODIA OPERATIONS | 2015-12-09 | — | — | CN | claimed |
| CN-102939195-B | Include the laser-light transparent PBT of organic additive | BASF SE (DE) | 2015-12-02 | — | — | CN | claimed |
| WO-2009080458-A1 | PROCESS FOR PREPARING DYEABLE POLYPROPYLENE | STELLINI PAOLO FRANCESCO (IT) | 2009-07-02 | — | — | WO | claimed |
| CN-1518570-A | Sulfoisophthalic acid solutions and related processes | 纳幕尔杜邦公司 | 2004-08-04 | — | — | CN | claimed |
| EP-4633831-A1 | PROCESS FOR PRODUCING LOW GLOSS COATING SURFACE BY RADIATION CURING | Covestro LLC (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4577608-A1 | PROCESS FOR PROVIDING LOW GLOSS COATINGS | Covestro (Netherlands) B.V. (NL) | 2025-07-02 | — | — | EP | disclosed |
| US-12110375-B2 | Compositions and foam compositions containing composite particles, articles, composite particles, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-10-08 | — | — | US | disclosed |
| WO-2024129632-A1 | PROCESS FOR PRODUCING LOW GLOSS COATING SURFACE BY RADIATION CURING | COVESTRO LLC (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-1486336-A | Polyester polymerization catalyst, polyester and process for producing polyester | 东洋纺织株式会社 | 2004-03-31 | — | — | CN | disclosed |
| CN-1114632-C | Acrylic acid modified aqueous sulfonated alkyd dispersion | EASTMAN CHEM CO (US) | 2003-07-16 | — | — | CN | disclosed |
| CN-1272854-A | Acrylic modified waterborne sulfonated alkyd dispersions | EASTMAN CHEM CO (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1050619-C | Biodegradable polyester copolymer, molded article using the same, and process for producing the molded article | KANEBO LTD (JP) | 2000-03-22 | — | — | CN | disclosed |
| CN-1114108-A | Biodegradable copolyester, molding produced therefrom, and process for producing the molding | KANEBO LTD (JP) | 1995-12-27 | — | — | CN | disclosed |