Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 7/20 | 0.42 |
| ▸ | CA1 known ✓ | P00915 | 6/20 | 0.42 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.39 |
| ▸ | DUSP5 | Q16690 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906244 | 0.95 | PTPN1 (0.42) | DUSP5PTPN1DUSP6CA2CA1 | |
| Zinc Ion SCHEMBL2469908 | 0.95 | PTPN1 (0.42) | DUSP5PTPN1DUSP6CA2CA1 | |
| SCHEMBL6856353 | 0.95 | PTPN1 (0.42) | DUSP5PTPN1DUSP6CA2CA1 | |
| Potassium Ion SCHEMBL2965238 | 0.95 | PTPN1 (0.42) | DUSP5PTPN1DUSP6CA2CA1 | |
| SCHEMBL6292110 | 0.95 | PTPN1 (0.42) | DUSP5PTPN1DUSP6CA2CA1 | |
| Lithium Ion SCHEMBL1645513 | 0.95 | PTPN1 (0.42) | DUSP5PTPN1DUSP6CA2CA1 | |
| SCHEMBL9574902 | 0.92 | LCK (0.53) | DUSP5PTPN1DUSP6CA2CA1 | |
| SCHEMBL5009688 | 0.90 | PTPN1 (0.38) | DUSP5PTPN1DUSP6CA2CA1 | |
| SCHEMBL7714612 | 0.88 | LCK (0.48) | DUSP5PTPN1DUSP6CA2CA1 | |
| Terephthalic Acid SCHEMBL8053920 | 0.87 | CA2 (0.48) | DUSP5PTPN1DUSP6CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534588-B2 | Multi-block copolyester ether thermoplastic elastomer foam, preparation method thereof, and sports shoe midsole made from the same | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2026-01-27 | — | — | US | claimed |
| WO-2024253080-A1 | SIZING AGENT FOR REINFORCING FIBERS AND REINFORCING FIBERS | 竹本油脂株式会社 | 2024-12-12 | — | — | WO | claimed |
| CN-118878848-A | Manganese (II) -ternary coordination polymer and preparation method and application thereof | 凯里学院 | 2024-11-01 | — | — | CN | claimed |
| CN-118290665-A | Preparation method of nonionic modified waterborne sulfonate-acrylic acid alkyd hybrid | 广东东方一哥新材料股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118272064-A | Gemini surfactant fracturing fluid and preparation method and application thereof | 陕西科技大学 | 2024-07-02 | — | — | CN | claimed |
| WO-2024128570-A1 | METHOD FOR PRODUCING CRYSTALLINE FIBER USING CARBOXYLIC ACID, SULFONIC ACID, PHOSPHORIC ACID, OR ACID SALT DERIVATIVE THEREOF | (주)비에이에너지 | 2024-06-20 | — | — | WO | claimed |
| CN-118186615-A | Preparation method and application of polyester nanofiber heterogeneous catalyst | 武汉纺织大学 | 2024-06-14 | — | — | CN | claimed |
| CN-117986556-A | Sulfonic polyester diol, aqueous polyurethane emulsion and preparation method thereof | 吉林天泽二氧化碳科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117865854-A | Production process of isophthalic acid-5-sodium sulfonate | 焦作润扬化工科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117843955-A | Polyimide resin and anode electrophoretic paint containing same | 浙江中科玖源新材料有限公司 | 2024-04-09 | — | — | CN | claimed |
| EP-1170375-A2 | Microbial transformation process for hydroxyaromatic compounds | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2002-01-09 | — | — | EP | claimed |
| US-6316586-B1 | DYEABILITY | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-11-13 | — | — | US | claimed |
| CN-1067122-C | Method for preparing colored polyamide fibers with contain polycarbonates and resultant fibers | DU PONT (US) | 2001-06-13 | — | — | CN | claimed |
| CN-1250455-A | Denatured thermoplastic resin product and method for producing the same | TEIJIN LTD (JP) | 2000-04-12 | — | — | CN | claimed |
| CN-1143984-A | Process for preparing colored polyamide fibers containing polycarbonate and fibers obtained | DU PONT (US) | 1997-02-26 | — | — | CN | claimed |
| US-5376618-A | Receiver layer contains copolyester from diols, dicarboxylic acids and long chain alkyl hydroxy-carboxylic acids | AGFA-GEVAERT, N.V. (BE) | 1994-12-27 | — | — | US | claimed |
| EP-0481130-B1 | Thermal dye sublimation transfer receiving element | AGFA GEVAERT NV (BE) | 1994-06-08 | — | — | EP | claimed |
| EP-0481130-A1 | Thermal dye sublimation transfer receiving element | AGFA-GEVAERT N.V. (BE) | 1992-04-22 | — | — | EP | claimed |
| US-4581398-A | Hydrolysis-resistant thermoplastic molding composition comprising high molecular weight polybutylene terephthalatepolyester and a dicarboxylic acid salt | HUELS AKTIENGESELLSCHAFT (DE) | 1986-04-08 | — | — | US | claimed |
| US-4330588-A | STAIN-RELEASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-05-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534588-B2 | Multi-block copolyester ether thermoplastic elastomer foam, preparation method thereof, and sports shoe midsole made from the same | SMC2, SMC1A, SMC3 | CA2 2896/4885CA1 2704/4885CA4 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.