Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 19/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26148692 | 0.89 | UGCG (0.52) | UGCGCYP3A4 | |
| SCHEMBL16455122 | 0.85 | UGCG (0.51) | UGCGCYP3A4 | |
| SCHEMBL18848618 | 0.82 | KMT2A (0.51) | UGCGCYP3A4P2RY12 | |
| SCHEMBL16455175 | 0.79 | UGCG (0.50) | UGCG | |
| SCHEMBL19466090 | 0.78 | KDM1A (0.55) | UGCG | |
| SCHEMBL18059489 | 0.78 | KDM1A (0.55) | UGCG | |
| SCHEMBL16455120 | 0.78 | UGCG (0.49) | UGCGCYP3A4 | |
| SCHEMBL18848697 | 0.76 | UGCG (0.52) | UGCGCYP3A4P2RY12 | |
| SCHEMBL19634350 | 0.76 | UGCG (0.41) | UGCGCYP3A4 | |
| SCHEMBL16455068 | 0.72 | KDM1A (0.46) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| WO-2015021128-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES INC. (US) | 2015-02-12 | — | — | WO | disclosed |