SCHEMBL16455229

SCHEMBL16455229

CCOC(=O)C(C)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(CO)NC(=O)CN(C(=O)CN(Cc1ccccc1)C(=O)CN(CCOC)C(C)=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 13/20 0.47
▸ SCTR P47872 1/20 0.46
▸ TFPI P10646 1/20 0.45
▸ APLNR P35414 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21386014 0.94 GLP1R (0.43) GLP1RSCTRTFPIAPLNR
SCHEMBL16455228 0.94 GLP1R (0.46) GLP1RSCTRTFPIAPLNR
SCHEMBL16455565 0.83 GLP1R (0.41) GLP1RSCTRTFPIAPLNR
SCHEMBL16455222 0.83 GLP1R (0.51) GLP1RSCTRTFPIAPLNR
SCHEMBL18116796 0.82 TFPI (0.51) GLP1RSCTRTFPIAPLNR
SCHEMBL18388624 0.80 APLNR (0.47) GLP1RSCTRTFPIAPLNR
SCHEMBL21386013 0.77 CTSL (0.49) GLP1R
SCHEMBL16455571 0.76 TFPI (0.45) GLP1RSCTRTFPIAPLNR
SCHEMBL30419550 0.74 GLP1R (0.55) GLP1RSCTRTFPI
SCHEMBL29445552 0.74 GLP1R (0.55) GLP1RSCTRTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421954-B2 Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same NEW YORK UNIVERSITY (US) 2019-09-24 — — US disclosed
US-20170015991-A1 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME NEW YORK UNIVERSITY 2017-01-19 — — US disclosed
US-9458449-B2 Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same NEW YORK UNIVERSITY (US) 2016-10-04 — — US disclosed
US-20150044189-A1 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME NEW YORK UNIVERSITY 2015-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421954-B2 Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same F12, RPS4Y1, NPY1R GLP1R 111/4885SCTR 424/4885TFPI 2247/4885
US-20170015991-A1 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME F12, RPS4Y1, NPY1R GLP1R 111/4885SCTR 424/4885TFPI 2247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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