SCHEMBL16455485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16455239	0.91	RXRA (0.43)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16455486	0.90	ALDH1A1 (0.39)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16455382	0.89	RXRA (0.47)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16455244	0.89	NR1H2 (0.42)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16452547	0.88	NPC1 (0.46)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16455245	0.87	HSP90AA1 (0.36)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16455300	0.86	S1PR1 (0.44)	NPC1RAB9ACA1CA2CA9
	SCHEMBL16455255	0.85	NR1H2 (0.48)	ALDH1A1NPC1RAB9ACA1CA2
	SCHEMBL16455644	0.84	NR1H2 (0.40)	HSP90AA1RXRANR1H2NR1H3HSP90B1
	SCHEMBL16455490	0.82	NR1H2 (0.40)	ALDH1A1NPC1RAB9ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.