SCHEMBL16455713

SCHEMBL16455713

CCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 4/20 1.00
▸ SPHK1 Q9NYA1 4/20 1.00
▸ LMNA P02545 4/20 1.00
▸ MAPT P10636 4/20 1.00
▸ GMNN O75496 3/20 1.00
▸ POLB P06746 3/20 1.00
▸ BLM P54132 3/20 1.00
▸ CETP P11597 3/20 1.00
▸ UBE2N P61088 3/20 1.00
▸ THPO P40225 2/20 1.00
▸ TP53 P04637 2/20 1.00
▸ CYP1A2 P05177 2/20 1.00
▸ MTOR P42345 1/20 1.00
▸ KDM4E B2RXH2 1/20 1.00
▸ CYP3A4 P08684 1/20 1.00
▸ HTT P42858 1/20 1.00
▸ CSNK1E P49674 1/20 0.54
▸ MEN1 O00255 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ GLA P06280 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Safingol SCHEMBL5061324 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL1900812 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
Dihydrospingosine SCHEMBL12563458 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
Safingol SCHEMBL6772 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL1131930 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL12330738 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL1131985 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL21660227 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL21431064 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL18127645 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025032499-A2 METHOD FOR THE ISOLATION OF GLYCOSPHINGOLIPIDS CARBOCODE S.A. (PT) 2025-02-13 — — WO claimed
CN-109596748-B Method for detecting metabolites of gandi capsules for treating diabetic nephropathy patients 上海交通大学医学院附属新华医院 2022-03-04 — — CN claimed
US-20210148933-A1 METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS Pepsis Limited (GB) 2021-05-20 — — US claimed
EP-3773919-A1 METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS Pepsis Limited (GB) 2021-02-17 — — EP claimed
WO-2019186141-A1 METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS Pepsis Limited (GB) 2019-10-03 — — WO claimed
US-12629421-B2 Artificially synthesized sphingosine derivative lipoid monomer and use of same for delivering nucleic acid BEIJING BAISHIHEKANG PHARMACEUTICAL TECHNOLOGY (BSJPHARMA) CO., LTD (CN) 2026-05-19 — — US disclosed
EP-4720029-A1 LIPID BLENDS Cataya Bio (Shanghai) Co., Ltd. (CN) 2026-04-08 — — EP disclosed
US-12590320-B2 Cellular models of and therapies for ocular diseases REFLECTION BIOTECHNOLOGIES LIMITED (HK) 2026-03-31 — — US disclosed
EP-4591884-A1 LIPID COMPOUND FOR NUCLEIC ACID DELIVERY, AND RELATED USE AND MEDICAMENT COMPRISING SAME Beijing Baishihekang Pharmaceutical Technology (Bsjpharma) Co., Ltd. (CN) 2025-07-30 — — EP disclosed
WO-2025133966-A1 PRODUCTION OF GLUCOSYLCERAMIDE CARBOCODE S.A (PT) 2025-06-26 — — WO disclosed
CN-111630170-B Cellular model of ocular disease and therapy for ocular disease 映像生物有限公司 2025-03-07 — — CN disclosed
WO-2025032497-A1 SIALYLATION METHOD CARBOCODE S.A. (PT) 2025-02-13 — — WO disclosed
US-11479798-B2 Recombinant host cell with altered membrane lipid composition BOEHRINGER INGELHEIM RCV GMBH & CO KG (AT) 2022-10-25 — — US disclosed
WO-2022192252-A1 USE OF NADOLOL TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY BLOCKAGE OF THE ARRESTIN-2 PATHWAY CHRONIC AIRWAY THERAPEUTICS LIMITED (AU) 2022-09-15 — — WO disclosed
US-20220125838-A1 IMMUNOMODULATORY GLYCOSPHINGOLIPIDS AND METHODS OF USE THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-04-28 — — US disclosed
US-20210148933-A1 METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS Pepsis Limited (GB) 2021-05-20 — — US disclosed
EP-3773919-A1 METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS Pepsis Limited (GB) 2021-02-17 — — EP disclosed
WO-2019186141-A1 METHODS AND ASSAYS FOR USE IN DIAGNOSIS OF LAMINITIS Pepsis Limited (GB) 2019-10-03 — — WO disclosed
WO-2019185038-A1 ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID 中国医学科学院基础医学研究所 2019-10-03 — — WO disclosed
US-20150045291-A1 LIPOPEPTIDE CONJUGATES COMPRISING SPHINGOLIPID AND HIV GP41 DERIVED PEPTIDES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2015-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629421-B2 Artificially synthesized sphingosine derivative lipoid monomer and use of same for delivering nucleic acid S1PR2, S1PR3, S1PR1 CYP2D6 4264/4885SPHK1 8/4885LMNA 77/4885
US-20220125838-A1 IMMUNOMODULATORY GLYCOSPHINGOLIPIDS AND METHODS OF USE THEREOF UGCG, B3GAT3, GALC CYP2D6 4646/4885SPHK1 111/4885LMNA 1471/4885
US-12590320-B2 Cellular models of and therapies for ocular diseases ALDH1A2, NR2E3, RBP4 CYP2D6 155/4885SPHK1 4875/4885LMNA 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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