Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455682 | 0.84 | POLB (0.56) | ALDH1A1SMN1; SMN2CNR2KDM4EKMT2A | |
| SCHEMBL17808299 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2PKMCNR1CNR2 | |
| SCHEMBL27034140 | 0.77 | MEN1 (0.43) | ALDH1A1CNR1CNR2KMT2A | |
| SCHEMBL14206953 | 0.77 | TDP1 (0.56) | ALDH1A1SMN1; SMN2PKMCNR1CNR2 | |
| SCHEMBL25371356 | 0.75 | KMT2A (0.39) | ALDH1A1CNR1CNR2KDM4EKMT2A | |
| SCHEMBL25316623 | 0.74 | THRB (0.38) | ALDH1A1CNR1CNR2KMT2ATSHR | |
| SCHEMBL25317998 | 0.74 | THRB (0.38) | ALDH1A1CNR1CNR2KMT2ATSHR | |
| SCHEMBL10080556 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KDM4EKMT2ATSHR | |
| SCHEMBL855566 | 0.74 | TSHR (0.47) | ALDH1A1SMN1; SMN2CNR1CNR2KDM4E | |
| SCHEMBL2927007 | 0.73 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2PKMKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611248-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-04-04 | — | — | US | disclosed |
| US-20160159767-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
| WO-2015018432-A1 | PYRROLONE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159767-A1 | CHEMICAL COMPOUNDS | DDT, CBR3, CYP1B1 | ALDH1A1 300/4885SMN1; SMN2 4478/4885PKM 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.