Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621390 | 0.87 | MAPT (0.43) | MAPTDRD2OPRM1DRD3SMN1; SMN2 | |
| SCHEMBL10299295 | 0.85 | DRD2 (0.36) | MAPTDRD2OPRM1DRD3SMN1; SMN2 | |
| SCHEMBL13270248 | 0.76 | DRD2 (0.41) | MAPTDRD2OPRM1DRD3SMN1; SMN2 | |
| SCHEMBL7561689 | 0.74 | — | — | |
| SCHEMBL13649569 | 0.74 | — | — | |
| SCHEMBL807052 | 0.74 | — | — | |
| SCHEMBL7526065 | 0.73 | MAPT (0.39) | MAPTDRD2OPRM1DRD3SMN1; SMN2 | |
| SCHEMBL1456257 | 0.73 | — | — | |
| SCHEMBL45387 | 0.73 | — | — | |
| SCHEMBL11091732 | 0.72 | CYP4F2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150044161-A1 | MULTIFUNCTIONAL POLYMERS | ISP INVESTMENTS INC. (US) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150044161-A1 | MULTIFUNCTIONAL POLYMERS | PUF60, PARG, PARN | MAPT 3417/4885DRD2 2678/4885OPRM1 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.