Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 12/20 | 0.40 |
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | PPARD | Q03181 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456500 | 0.92 | PPARA (0.44) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL16456489 | 0.85 | DRD3 (0.42) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6076269 | 0.84 | PGR (0.52) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6076220 | 0.84 | PGR (0.51) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6076606 | 0.82 | ADORA3 (0.51) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6075620 | 0.82 | PGR (0.48) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL542804 | 0.82 | PGR (0.50) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6076674 | 0.81 | PGR (0.42) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6075488 | 0.81 | PPARA (0.43) | PGRADORA3CHRM1TBXA2RPTGS1 | |
| SCHEMBL6076953 | 0.80 | PPARG (0.41) | PGRADORA3CHRM1TBXA2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250323-B1 | Compounds having hypolipidemic and hypocholesterolemic activities, process for their preparation and pharmaceutical compositions containing them | CADILA HEALTHCARE LTD (IN) | 2014-01-01 | — | — | EP | claimed |