Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 5/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16457052 | 0.92 | NR3C2 (0.49) | NR3C2AVPR2OXTRAVPR1AP2RX4 | |
| SCHEMBL16457242 | 0.90 | NR3C2 (0.48) | NR3C2AVPR2OXTRAVPR1ALMNA | |
| SCHEMBL2547086 | 0.88 | NR3C2 (0.48) | NR3C2AVPR2OXTRAVPR1ALMNA | |
| SCHEMBL16456865 | 0.87 | NR3C2 (0.59) | NR3C2AVPR2OXTRAVPR1ALMNA | |
| SCHEMBL2360202 | 0.86 | NR3C2 (0.58) | NR3C2AVPR2OXTRAVPR1ALMNA | |
| SCHEMBL16457142 | 0.86 | NR3C2 (0.54) | NR3C2AVPR2OXTRAVPR1ALMNA | |
| SCHEMBL2359769 | 0.83 | NR3C2 (0.46) | NR3C2AVPR2OXTRAVPR1AMAPT | |
| SCHEMBL16456948 | 0.82 | NR3C2 (0.57) | NR3C2P2RX4MAPTCA12CA2 | |
| SCHEMBL16457080 | 0.81 | NR3C2 (0.46) | NR3C2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16456899 | 0.81 | NR3C2 (0.46) | NR3C2AVPR2OXTRAVPR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |