Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16457022 | 0.94 | NR3C2 (0.62) | NR3C2SLC1A3SLC1A2SLC1A1LRRK2 | |
| SCHEMBL16457052 | 0.88 | NR3C2 (0.49) | NR3C2SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL2359256 | 0.87 | NR3C2 (0.75) | NR3C2LRRK2MAPTMAPK1NPSR1 | |
| SCHEMBL2551383 | 0.87 | NR3C2 (0.74) | NR3C2MAPTMAPK1NPSR1PTGES2 | |
| SCHEMBL16456970 | 0.86 | NR3C2 (0.52) | NR3C2SLC1A3SLC1A2SLC1A1LRRK2 | |
| SCHEMBL16457142 | 0.84 | NR3C2 (0.54) | NR3C2SLC1A3SLC1A2SLC1A1LRRK2 | |
| SCHEMBL16458046 | 0.82 | NR3C2 (0.52) | NR3C2SLC1A3SLC1A2SLC1A1LRRK2 | |
| SCHEMBL16457250 | 0.82 | NR3C2 (0.44) | NR3C2MAPTCA12CA2CA9 | |
| SCHEMBL2551428 | 0.81 | NR3C2 (0.74) | NR3C2MAPTNPSR1CA12CA2 | |
| SCHEMBL16456941 | 0.81 | NR3C2 (0.60) | NR3C2MAPTMAPK1NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349996-B1 | 1-PHENYLPYRROLE COMPOUNDS | EXELIXIS INC (US) | 2014-01-01 | — | — | EP | disclosed |