Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942073 | 0.96 | LMNA (0.35) | LMNAMAPTHPGDCTSKALDH1A1 | |
| SCHEMBL3645141 | 0.90 | MAPT (0.35) | LMNAMAPTHPGDCTSKALDH1A1 | |
| SCHEMBL4481936 | 0.81 | TP53 (0.42) | MAPT | |
| SCHEMBL1645785 | 0.75 | ALDH1A1 (0.41) | HPGDALDH1A1 | |
| SCHEMBL334542 | 0.74 | TSHR (0.39) | LMNAMAPTCTSKALDH1A1 | |
| SCHEMBL9284085 | 0.72 | PLG (0.38) | LMNAMAPT | |
| SCHEMBL2988848 | 0.71 | LMNA (0.41) | LMNAHPGDCTSKALDH1A1 | |
| SCHEMBL7843971 | 0.71 | LMNA (0.41) | LMNAHPGDCTSKALDH1A1 | |
| SCHEMBL2986132 | 0.71 | LMNA (0.41) | LMNAHPGDCTSKALDH1A1 | |
| SCHEMBL28483461 | 0.70 | ANPEP (0.38) | LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |