Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637152 | 0.88 | GAA (0.64) | KMT2AMEN1GAAPOLBGFER | |
| SCHEMBL28607272 | 0.87 | GAA (0.70) | KMT2AGAAPOLBGFERRAB9A | |
| SCHEMBL28618230 | 0.87 | CHEK1 (0.63) | KMT2AMEN1GAAPOLBGFER | |
| SCHEMBL6169172 | 0.85 | MEN1 (0.83) | KMT2AMEN1GAAPOLBSMN1; SMN2 | |
| SCHEMBL28607667 | 0.84 | POLB (0.64) | KMT2AGAAPOLBGFERRAB9A | |
| SCHEMBL27321163 | 0.84 | GAA (0.60) | KMT2AMEN1GAAPOLBGFER | |
| SCHEMBL6169126 | 0.84 | ALDH1A1 (0.80) | KMT2AMEN1GAARAB9ASMN1; SMN2 | |
| SCHEMBL3653095 | 0.84 | EPHX2 (0.77) | KMT2AMEN1POLBSMN1; SMN2EPHX2 | |
| SCHEMBL7850198 | 0.83 | POLB (0.73) | KMT2AMEN1GAAPOLBPARP14 | |
| SCHEMBL8181946 | 0.83 | MEN1 (0.75) | KMT2AMEN1GAAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4665239-B2 | — | — | 2011-04-06 | — | — | JP | claimed |