Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639241 | 0.93 | KDM4E (0.60) | GAAPOLBGFERKMT2ALMNA | |
| SCHEMBL28618230 | 0.91 | CHEK1 (0.63) | GAAPOLBGFERKMT2ALMNA | |
| SCHEMBL28607272 | 0.91 | GAA (0.70) | GAAPOLBGFERKMT2ALMNA | |
| SCHEMBL28607667 | 0.89 | POLB (0.64) | GAAPOLBGFERKMT2ALMNA | |
| SCHEMBL8638027 | 0.88 | MEN1 (0.67) | GAAPOLBGFERKMT2ALMNA | |
| SCHEMBL1645810 | 0.88 | KMT2A (0.71) | GAAPOLBGFERKMT2ALMNA | |
| SCHEMBL8637193 | 0.87 | KMT2A (0.60) | GAAKMT2ALMNAMEN1SMN1; SMN2 | |
| SCHEMBL8639573 | 0.83 | RAB9A (0.70) | GAAPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8638900 | 0.83 | MAPK8 (0.65) | GAAPOLBKMT2ALMNAMEN1 | |
| SCHEMBL8639229 | 0.81 | MAPT (0.71) | GAAGFERKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |