Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471989 | 0.78 | LMNA (0.66) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL16460055 | 0.76 | LMNA (0.46) | LMNAKDM4EHTT | |
| SCHEMBL16459165 | 0.76 | LMNA (0.62) | LMNAKDM4EHTT | |
| SCHEMBL16459876 | 0.73 | LMNA (0.38) | LMNAKDM4EALDH1A1 | |
| SCHEMBL16475554 | 0.72 | LMNA (0.39) | LMNAKDM4EALDH1A1 | |
| SCHEMBL16459946 | 0.71 | LMNA (0.46) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL16459758 | 0.71 | LMNA (0.47) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL16459658 | 0.71 | HPGD (0.39) | LMNAKDM4EALDH1A1 | |
| SCHEMBL23480876 | 0.70 | LMNA (0.46) | LMNAKDM4EALDH1A1HTT | |
| SCHEMBL16459397 | 0.70 | LMNA (0.46) | LMNAKDM4EALDH1A1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | MINK1, MELK, MRPL21 | LMNA 1949/4885KDM4E 3282/4885ALDH1A1 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.