Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.51 |
| ▸ | DRD2 | P14416 | 7/20 | 0.51 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | DRD4 | P21917 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HTR7 | P34969 | 4/20 | 0.51 |
| ▸ | DRD1 | P21728 | 3/20 | 0.49 |
| ▸ | DRD5 | P21918 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682870 | 0.83 | GAA (0.57) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL22197868 | 0.81 | DRD3 (0.46) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL3398170 | 0.81 | GAA (0.55) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL3398177 | 0.80 | TLR7 (0.46) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL1725429 | 0.80 | MAP4K4 (0.57) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL23246010 | 0.79 | ALDH1A1 (0.44) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL29618438 | 0.79 | ALDH1A1 (0.44) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL19998348 | 0.79 | GRIN2D (0.59) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL29499599 | 0.79 | GRIN2D (0.59) | DRD3DRD2HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL1724621 | 0.79 | MAP4K4 (0.56) | DRD3DRD2HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |