SCHEMBL16461564

SCHEMBL16461564

CC(CCCN)CN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PRMT8 Q9NR22 1/20 0.43
HTR2A P28223 2/20 0.43
HRH1 P35367 1/20 0.43
AOC3 Q16853 2/20 0.40
MAOA P21397 1/20 0.40
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRK1 P41145 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CNR2 P34972 1/20 0.38
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22844144 0.83 KMT2A (0.39) HTR2AADRA2BADRA2CSLC6A2SLC6A4
SCHEMBL28623853 0.82 AOC3 (0.45) CARM1PRMT6PRMT8HTR2AAOC3
SCHEMBL19628486 0.77 TAAR1 (0.52) HTR2AHRH1MAOASLC6A2SLC6A4
SCHEMBL14397661 0.75 TRPA1 (0.46) HTR2AAOC3ADRA2BADRA2CSLC6A2
SCHEMBL1839564 0.74 SLC6A2 (0.54) CARM1PRMT6PRMT8HTR2AAOC3
SCHEMBL14085920 0.74 SLC6A2 (0.54) CARM1PRMT6PRMT8HTR2AAOC3
SCHEMBL1839568 0.74 SLC6A2 (0.54) CARM1PRMT6PRMT8HTR2AAOC3
SCHEMBL17508104 0.74 CARM1 (0.45) CARM1PRMT6PRMT8HTR2AHRH1
SCHEMBL14006363 0.74 BCHE (0.51) HTR2AAOC3ADRA2BADRA2CSLC6A2
SCHEMBL15301724 0.73 BCHE (0.43) HTR2AAOC3ADRA2BADRA2CSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212287-B2 Low-emission hardener for epoxy resins SIKA TECHNOLOGY AG (CH) 2015-12-15 US disclosed
US-20140107313-A1 LOW-EMISSION HARDENER FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2014-04-17 US disclosed