SCHEMBL19628486

SCHEMBL19628486

CC(CCCN)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.52
SLC6A2 P23975 2/20 0.52
MAOA P21397 2/20 0.52
SIGMAR1 Q99720 2/20 0.52
CYP2A6 P11509 2/20 0.52
SLC6A4 P31645 1/20 0.52
SLC6A3 Q01959 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
HTR2A P28223 2/20 0.50
HRH1 P35367 1/20 0.50
CYP2D6 P10635 1/20 0.48
EPHX1 P07099 1/20 0.45
SLC18A2 Q05940 1/20 0.44
ALDH1A1 P00352 1/20 0.42
TRPA1 O75762 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8512221 0.94 TAAR1 (0.50) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL21242301 0.92 TAAR1 (0.48) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL23934035 0.91 TAAR1 (0.47) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL8524202 0.88 TAAR1 (0.56) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL11990712 0.88 TAAR1 (0.56) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL6824286 0.82 CSNK1E (0.49) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL7937685 0.82 TRPA1 (0.53) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL6286870 0.82 SIGMAR1 (0.55) TAAR1SLC6A2MAOASIGMAR1CYP2A6
SCHEMBL9418115 0.80 SIGMAR1 (0.56) SIGMAR1
SCHEMBL6693090 0.80 CSNK1E (0.56) TAAR1SLC6A2MAOASIGMAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112153807-A Polyimide film, metal-clad laminate, and flexible circuit board 日铁化学材料株式会社 2020-12-29 CN disclosed
WO-2017198775-A1 STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES ETH ZURICH (CH) 2017-11-23 WO disclosed