SCHEMBL16463192

SCHEMBL16463192

NC(O)(CCc1ccccc1)C(=O)OC1C2CC3CC(C2)CC1C3

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.44
GRM2 Q14416 2/20 0.44
GRM3 Q14832 2/20 0.44
HSD11B1 P28845 2/20 0.40
CCKBR P32239 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341497 0.73 SRC (0.45) GRM2GRM3
SCHEMBL6344201 0.73 SRC (0.45) GRM2GRM3
SCHEMBL6345448 0.72 TSHR (0.49) GRM2GRM3
SCHEMBL27463604 0.72 TSHR (0.49) GRM2GRM3
SCHEMBL7441576 0.70 GRM2 (0.53) GRM2GRM3
SCHEMBL8219953 0.70 GRM2 (0.53) GRM2GRM3
SCHEMBL11088109 0.70 GRM2 (0.53) GRM2GRM3
SCHEMBL28307236 0.69 GRM2 (0.47) GRM2GRM3
SCHEMBL19798402 0.68 EPHX2 (0.50) EPHX2HSD11B1
SCHEMBL18287604 0.66 HSD11B1 (0.44) EPHX2HSD11B1CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014057495-A1 A PROCESS FOR INDUSTRIAL PREPARATION OF [(S)-N-TERT BUTOXYCARBONYL-3-HYDROXY]ADAMANTYLGLYCINE LEE PHARMA LIMITED (IN) 2014-04-17 WO claimed