Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP19 | O94966 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27603667 | 0.89 | USP19 (0.48) | ALDH1A1USP19CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL38659223 | 0.88 | KDM4E (0.45) | ALDH1A1USP19CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL14833618 | 0.87 | CHRNA7 (0.45) | ALDH1A1CHRNA7CHRNB2CHRNA4KDM4E | |
| Hydrochloric Acid SCHEMBL2234958 | 0.87 | USP19 (0.45) | USP19KDM4EBLMALOX15 | |
| SCHEMBL27176422 | 0.84 | KDM4E (0.49) | ALDH1A1USP19CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL16462634 | 0.83 | MAOA (0.42) | USP19CHRNA7CHRNB2CHRNA4DPP4 | |
| SCHEMBL20555983 | 0.83 | DPP4 (0.36) | USP19CHRNB2CHRNA4DPP4CHRNB4 | |
| SCHEMBL2386164 | 0.83 | DPP4 (0.47) | USP19DPP4 | |
| Hydrochloric Acid SCHEMBL28773228 | 0.82 | DPP4 (0.46) | USP19DPP4 | |
| SCHEMBL15529641 | 0.82 | CHRNA7 (0.51) | ALDH1A1CHRNA7CHRNB2CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906221-A1 | UREA AND AMIDE DERIVATIVES OF AMINOALKYLPIPERAZINES AND USE THEREOF | Southern Research Institute (US) | 2015-08-19 | — | — | EP | claimed |
| WO-2014059265-A1 | UREA AND AMIDE DERIVATIVES OF AMINOALKYLPIPERAZINES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2014-04-17 | — | — | WO | claimed |