Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.59 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473930 | 0.83 | DHFR (0.58) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| SCHEMBL27612323 | 0.81 | CSNK1A1 (0.55) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| Hydrochloric Acid SCHEMBL15487768 | 0.81 | DHFR (0.56) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| SCHEMBL24500397 | 0.80 | DPP4 (0.67) | CSNK1A1CLK4ADORA2AADORA1KDM4E | |
| SCHEMBL27716588 | 0.79 | CSNK1A1 (0.53) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| Ampyrimine SCHEMBL1230765 | 0.79 | DHFR (0.61) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| SCHEMBL26708031 | 0.78 | KDM4E (0.61) | CSNK1A1CLK4ADORA2ANUDT1ADORA1 | |
| SCHEMBL28151078 | 0.78 | DHFR (0.57) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| SCHEMBL28145391 | 0.77 | ADORA2A (0.59) | CSNK1A1CLK4ADORA2ANUDT1DHFR | |
| SCHEMBL28447630 | 0.77 | CSNK1A1 (0.50) | CSNK1A1CLK4ADORA2ANUDT1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906191-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | Henkel AG&Co. KGAA (DE) | 2015-08-19 | — | — | EP | claimed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | claimed |