Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.40 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 6/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463835 | 0.98 | CDK1 (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16463774 | 0.90 | CDK1 (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16462943 | 0.88 | CDK1 (0.38) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16463779 | 0.85 | DHFR (0.37) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11699945 | 0.84 | CDK1 (0.54) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16462790 | 0.83 | DHFR (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16463304 | 0.82 | DHFR (0.34) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16482192 | 0.81 | CDK1 (0.37) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL16464928 | 0.81 | NOS1 (0.34) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11700870 | 0.80 | CDK1 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906191-B1 | HAIR DYE CONTAINING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2018-03-28 | — | — | EP | claimed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | claimed |
| EP-2906191-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | Henkel AG&Co. KGAA (DE) | 2015-08-19 | — | — | EP | claimed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | claimed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | claimed |
| EP-2906191-B1 | HAIR DYE CONTAINING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| US-9364408-B2 | Hair dye agent comprising aminopyrimidine derivatives | HENKEL AG & CO. KGAA (DE) | 2016-06-14 | — | — | US | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2015-07-30 | — | — | US | disclosed |
| WO-2014056760-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150209258-A1 | HAIR DYE AGENT COMPRISING AMINOPYRIMIDINE DERIVATIVES | KRT18, DPYD, DHFR | CDK1 507/4885CCNB1 239/4885CCNA2 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.