Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034656 | 0.82 | GAA (0.51) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL28387335 | 0.81 | GAA (0.50) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL28390747 | 0.81 | GAA (0.50) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL27886361 | 0.81 | GAA (0.53) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL28430240 | 0.80 | GAA (0.49) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL16463217 | 0.80 | GAA (0.49) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL27678532 | 0.79 | GAA (0.51) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL434619 | 0.75 | GAA (0.53) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL16463218 | 0.74 | GAA (0.42) | GAAPKMMAPTKDM4ETDP1 | |
| SCHEMBL28324772 | 0.74 | RIPK1 (0.53) | GAAPKMMAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014056333-A9 | IMMUNE RECEPTOR MODIFIER CONJUGATE AND PREPARATION METHOD AND USE THEREOF, COUPLING PRECURSOR FOR PREPARING SAME, AND COMPOUND FOR SYNTHESIZING COUPLING PRECURSOR | 深圳大学 | 2015-04-30 | — | — | WO | disclosed |
| WO-2014056333-A1 | IMMUNE RECEPTOR MODIFIER CONJUGATE AND PREPARATION METHOD AND USE THEREOF, COUPLING PRECURSOR FOR PREPARING SAME, AND COMPOUND FOR SYNTHESIZING COUPLING PRECURSOR | 深圳大学 (CN) | 2014-04-17 | — | — | WO | disclosed |