Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 13/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20163108 | 0.81 | HDAC2 (0.76) | HDAC2HDAC1HDAC3 | |
| SCHEMBL651882 | 0.81 | HDAC1 (0.57) | HDAC2HDAC1HDAC3KMT2AMEN1 | |
| SCHEMBL13737740 | 0.78 | HDAC2 (0.71) | HDAC2HDAC1HDAC3 | |
| SCHEMBL13735115 | 0.78 | HDAC1 (0.55) | HDAC2HDAC1HDAC3 | |
| SCHEMBL1646305 | 0.77 | AAK1 (0.47) | HDAC2HDAC1HDAC3AAK1 | |
| SCHEMBL7467565 | 0.77 | AAK1 (0.61) | HDAC2HDAC1HDAC3AAK1 | |
| SCHEMBL31708955 | 0.76 | ALDH1A1 (0.59) | HDAC2HDAC1HDAC3KMT2AMEN1 | |
| Hydrogen Peroxide SCHEMBL2904527 | 0.74 | TDP1 (0.88) | HDAC2HDAC1HDAC3KMT2AMEN1 | |
| Hydrogen Peroxide SCHEMBL2904525 | 0.74 | TDP1 (0.88) | HDAC2HDAC1HDAC3KMT2AMEN1 | |
| SCHEMBL9796871 | 0.72 | KMT2A (0.58) | KMT2AMEN1TDP1KDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050146-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |