Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.88 |
| ▸ | MEN1 | O00255 | 3/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL2904527 | 1.00 | TDP1 (0.88) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL23855 | 0.94 | TDP1 (1.00) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL29349835 | 0.94 | TDP1 (1.00) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| Hydrogen Sulfide SCHEMBL7866760 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL504482 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| Methane SCHEMBL1599658 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| SCHEMBL8745318 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| Water SCHEMBL3137651 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| Water SCHEMBL10589317 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL874057 | 0.90 | TDP1 (0.93) | TDP1KMT2AMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712237-B1 | Erythropoietin solution preparation stabilized with leucine or glutamic acid | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-20090041753-A1 | Cytokine signaling | CASE WESTERN RESERVE UNIVERSITY | 2009-02-12 | — | — | US | disclosed |
| EP-1712237-A2 | Erythropoietin solution preparation stabilized with leucine, glutamic acid or lysine | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-10-18 | — | — | EP | disclosed |
| EP-0909564-B1 | ERYTHROPOIETIN SOLUTION PREPARATION STABILIZED WITH AMINO ACIDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-7011825-B2 | Erythropoietin solution preparation | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-03-14 | — | — | US | disclosed |
| WO-2004039395-A1 | IMMUNNOEVASIVE AGENT FOR PREVENTING GRAFT REJECTION | SHIRAKI KATSUYA (JP) | 2004-05-13 | — | — | WO | disclosed |
| US-20040087507-A1 | Erythropoietin solution preparation | YAMAZAKI TADAO (JP) | 2004-05-06 | — | — | US | disclosed |
| US-6627187-B2 | Containing an amino acid as a stabilizer; long term storage stability | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-09-30 | — | — | US | disclosed |
| US-20010055582-A1 | Erythropoietin solution preparation | YAMAZAKI TADAO (JP) | 2001-12-27 | — | — | US | disclosed |
| US-6277367-B1 | CONTAINING ERYTHROPOIETIN IN COMBINATION WITH A STABILIZER, SAID STABILIZER IS ONE OR MORE AMINO ACIDS SELECTED FROM THE GROUP CONSISTING OF TRYPTOPHAN AND SERINE AND THEIR SALTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6120761-A | MIXTURE CONTAINING HISTIDINE STABILIZER | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0909564-A1 | ERYTHROPOIETIN SOLUTION PREPARATION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-04-21 | — | — | EP | disclosed |