SCHEMBL1646754

SCHEMBL1646754

Nc1cnccc1CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979284 0.83 AOC1 (0.61)
SCHEMBL29964442 0.82
SCHEMBL1930789 0.82
SCHEMBL5748797 0.79
SCHEMBL30210557 0.79
SCHEMBL12833330 0.79
SCHEMBL3819598 0.79
SCHEMBL29900474 0.78 AOC1 (0.43)
SCHEMBL6249306 0.78 AOC1 (0.43)
SCHEMBL13674751 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751906-A Bio-based hyperbranched epoxy resin/bisphenol A epoxy resin composite resin containing imide structure 中南民族大学 2025-04-04 CN claimed
WO-2009023669-A1 SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF JANSSEN PHARMACEUTICA N.V. (BE) 2009-02-19 WO claimed
US-20090048295-A1 SUBSTITUTED 5,6,7,8-TETRAHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE THEREOF JANSSEN PHARMACEUTICE N.V. (BE) 2009-02-19 US claimed
US-20250205348-A1 NOVEL PEPTIDIC LINKERS AND CRYPTOPHYCIN CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE SANOFI (FR) 2025-06-26 US disclosed
CN-119751906-A Bio-based hyperbranched epoxy resin/bisphenol A epoxy resin composite resin containing imide structure 中南民族大学 2025-04-04 CN disclosed
US-20250109148-A1 HETEROCYCLIC GLP-1 AGONISTS SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD. (CN) 2025-04-03 US disclosed
CN-119343339-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2025-01-21 CN disclosed
EP-4469444-A1 HETEROCYCLIC GLP-1 AGONISTS Gasherbrum Bio, Inc. (US) 2024-12-04 EP disclosed
WO-2024199069-A1 POLYARYL-CONTAINING MACROCYCLIC COMPOUND AND USE THEREOF 浙江养生堂天然药物研究所有限公司 2024-10-03 WO disclosed
CN-118724916-A Polyaryl-containing macrocyclic compounds and uses thereof 浙江养生堂天然药物研究所有限公司 2024-10-01 CN disclosed
US-11998611-B2 Cryptophycin antibody conjugates for the treatment of cancer SANOFI (FR) 2024-06-04 US disclosed
EP-1539742-A1 INDOLE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS SCHERING CORPORATION (US) 2005-06-15 EP disclosed
US-20040097513-A1 Novel non-imidazole compounds ASLANIAN ROBERT G (US) 2004-05-20 US disclosed
US-6720328-B2 TREATING ALLERGY, ALLERGY-INDUCED AIRWAY RESPONSES, AND CONGESTION (E.G., NASAL CONGESTION) SCHERING CORPORATION 2004-04-13 US disclosed
US-20040019099-A1 Treating inflammatory diseases, allergic conditions and central nervous system disorders SCHERING CORPORATION 2004-01-29 US disclosed
WO-2004000831-A1 INDOLE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS SCHERING CORPORATION (US) 2003-12-31 WO disclosed
EP-1326858-A2 PIPERIDINE COMPOUNDS AS ANTI-ALLERGIC Schering Corporation (US) 2003-07-16 EP disclosed
US-20030109682-A1 Maytansines and maytansine conjugates SANTI DANIEL (US) 2003-06-12 US disclosed
US-20030045519-A1 Novel non-imidazole compounds SCHERING CORPORATION 2003-03-06 US disclosed
WO-2002032893-A2 PIPERIDINE COMPOUNDS AS ANTI-ALLERGIC SCHERING CORPORATION (US) 2002-04-25 WO disclosed