Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934566 | 0.79 | HCRTR1 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL1293968 | 0.78 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL17938124 | 0.76 | ALDH1A1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL17938125 | 0.76 | ALDH1A1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL21612081 | 0.75 | EGLN1 (0.43) | HCRTR1HCRTR2EGLN1 | |
| SCHEMBL16766291 | 0.75 | CDC7 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL16766249 | 0.75 | CDC7 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL1914704 | 0.74 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL2193248 | 0.74 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL934131 | 0.74 | HCRTR1 (0.36) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050146-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |