Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193248 | 0.81 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL1293968 | 0.81 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL934131 | 0.81 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL2386864 | 0.81 | PRKCZ (0.31) | — | |
| SCHEMBL1914704 | 0.81 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL1646776 | 0.79 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL1914065 | 0.77 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL1293811 | 0.76 | SCN10A (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL1914123 | 0.74 | KDM5A (0.31) | — | |
| SCHEMBL17938124 | 0.74 | ALDH1A1 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009084-A2 | BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-01-20 | — | — | WO | disclosed |