SCHEMBL16468221

SCHEMBL16468221

Cc1ccc(CO/N=C(\Cc2ccccc2)c2ccc(OCC(=O)N3CCOCC3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 6/20 0.57
HPGD P15428 4/20 0.57
ALDH1A1 P00352 3/20 0.57
USP2 O75604 2/20 0.57
SMN1; SMN2 Q16637 4/20 0.52
GPR183 P32249 1/20 0.51
CYP2C9 P11712 1/20 0.49
POLB P06746 2/20 0.49
GAA P10253 3/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16468222 1.00 FKBP1A (0.57) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15543990 0.94 ALDH1A1 (0.62) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15543992 0.94 ALDH1A1 (0.62) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15543996 0.93 FKBP1A (0.60) FKBP1AHPGDALDH1A1SMN1; SMN2GPR183
SCHEMBL15543994 0.93 FKBP1A (0.60) FKBP1AHPGDALDH1A1SMN1; SMN2GPR183
SCHEMBL15560634 0.91 ALDH1A1 (0.60) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15561014 0.91 FKBP1A (0.60) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15560633 0.91 ALDH1A1 (0.60) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15561016 0.91 FKBP1A (0.60) FKBP1AHPGDALDH1A1USP2SMN1; SMN2
SCHEMBL15542902 0.90 GAA (0.52) FKBP1AHPGDALDH1A1USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150051144-A1 COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES CADILA HEALTHCARE LTD (IN) 2015-02-19 US claimed
US-20150051144-A1 COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES CADILA HEALTHCARE LTD (IN) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051144-A1 COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES PCSK9, HMGCR, CETP FKBP1A 1033/4885HPGD 847/4885ALDH1A1 1508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.