Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231525 | 0.94 | ALDH1A1 (0.49) | ALDH1A1POLBGSK3BMAPTL3MBTL1 | |
| SCHEMBL1645876 | 0.79 | PTPRC (0.48) | ALDH1A1POLBMAPTL3MBTL1MEN1 | |
| SCHEMBL395369 | 0.78 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTL3MBTL1KMT2A | |
| SCHEMBL5491859 | 0.75 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTL3MBTL1KMT2A | |
| SCHEMBL429356 | 0.73 | ALDH1A1 (0.65) | ALDH1A1POLBMAPTL3MBTL1RECQL | |
| SCHEMBL28359072 | 0.72 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTGAAKDM4E | |
| SCHEMBL2230940 | 0.72 | GSK3B (0.53) | ALDH1A1POLBGSK3BMAPTMEN1 | |
| SCHEMBL27030782 | 0.70 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL7221510 | 0.69 | ATM (0.65) | ALDH1A1POLBGSK3BMAPTL3MBTL1 | |
| SCHEMBL17055329 | 0.69 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303329-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |