⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697735 | 0.73 | — | — | |
| SCHEMBL7215917 | 0.67 | — | — | |
| SCHEMBL866248 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL18422639 | 0.65 | — | — | |
| SCHEMBL2398119 | 0.64 | — | — | |
| SCHEMBL7545259 | 0.64 | MAPT (0.43) | — | |
| SCHEMBL27388424 | 0.64 | — | — | |
| SCHEMBL3035541 | 0.62 | — | — | |
| SCHEMBL16830833 | 0.62 | — | — | |
| SCHEMBL29526981 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313588-A1 | NOVEL PYRROLOPYRIMIDINONE CARBOXAMIDE COMPOUND FOR INHIBITING CDK, STEREOISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING SAME AS ACTIVE INGREDIENT | UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION (KR) | 2025-10-09 | — | — | US | claimed |
| CN-115073470-B | Pyrrolopyrimidinone derivative, and preparation method and application thereof | 南京中瑞药业有限公司 | 2025-02-11 | — | — | CN | claimed |
| US-20240208912-A1 | MTA-Cooperative PRMT5 Inhibitors | MIRATI THERAPEUTICS INC (US) | 2024-06-27 | — | — | US | claimed |
| EP-4304720-A1 | MTA-COOPERATIVE PRMT5 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| WO-2023219427-A1 | NOVEL PYRROLOPYRIMIDINONE CARBOXAMIDE COMPOUND FOR INHIBITING CDK, STEREOISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING SAME AS ACTIVE INGREDIENT | 서울대학교산학협력단 | 2023-11-16 | — | — | WO | claimed |
| CN-114761410-B | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | claimed |
| WO-2022213932-A1 | PYRROLOPYRIMIDINONE COMPOUND AND APPLICATION THEREOF | 广州必贝特医药股份有限公司 | 2022-10-13 | — | — | WO | claimed |
| CN-115073470-A | Pyrrolopyrimidinone derivative and preparation method and application thereof | 南京中瑞药业有限公司 | 2022-09-20 | — | — | CN | claimed |
| WO-2022192745-A1 | MTA-COOPERATIVE PRMT5 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-09-15 | — | — | WO | claimed |
| US-20100069632-A1 | SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SK CHEMICALS CO., LTD (KR) | 2010-03-18 | — | — | US | claimed |
| JP-2009542633-A | — | — | 2009-12-03 | — | — | JP | claimed |
| EP-2038282-A1 | SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SK Chemicals, Co., Ltd. (KR) | 2009-03-25 | — | — | EP | claimed |
| WO-2008004796-A1 | SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2008-01-10 | — | — | WO | claimed |
| EP-1551962-A4 | MITOTIC KINESIN BINDING SITE | MERCK & CO INC (US) | 2007-08-01 | — | — | EP | claimed |
| EP-1551962-A2 | MITOTIC KINESIN BINDING SITE | Merck & Co., Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| WO-2004004652-A2 | MITOTIC KINESIN BINDING SITE | MERCK & CO., INC. (US) | 2004-01-15 | — | — | WO | claimed |
| US-6346359-B1 | FORMS COLOR BY REACTION WITH DIAZONIUM SALT; COLORFASTNESS, STORAGE STABILITY, SHELF LIFE; PURPLE AND CYAN HUES | FUJI PHOTO FILM CO., LTD. (JP) | 2002-02-12 | — | — | US | claimed |
| EP-0682027-B1 | Pyrrolopyrimidine derivatives with antiproliferative action | CIBA GEIGY AG (CH) | 1997-10-15 | — | — | EP | claimed |
| EP-0682027-A1 | Pyrrolopyrimidine derivatives with antiproliferative action | CIBA-GEIGY AG (CH) | 1995-11-15 | — | — | EP | claimed |