SCHEMBL16468643

SCHEMBL16468643

C=C(C(=O)O)C(C)C(O)CC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
TP53 P04637 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4420162 0.82 LMNA (0.39) TET2TET3TET1TP53
SCHEMBL6891214 0.80 TDP1 (0.35) TSHR
SCHEMBL7665622 0.75
SCHEMBL97738 0.75
SCHEMBL4744383 0.75
SCHEMBL18562028 0.75
SCHEMBL5499838 0.75
SCHEMBL12590197 0.75
SCHEMBL667584 0.75
SCHEMBL4228879 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10561733-B2 Process for producing nanoparticles laden with active ingredient MERCK PATENT GMBH (DE) 2020-02-18 US claimed
EP-2819659-B1 PROCESS FOR PRODUCING NANOPARTICLES LADEN WITH ACTIVE INGREDIENT MERCK PATENT GMBH (DE) 2018-05-30 EP claimed
US-20150051181-A1 PROCESS FOR PRODUCING NANOPARTICLES LADEN WITH ACTIVE INGREDIENT MERCK PATENT GMBH (DE) 2015-02-19 US claimed
US-10561733-B2 Process for producing nanoparticles laden with active ingredient MERCK PATENT GMBH (DE) 2020-02-18 US disclosed
US-20150051181-A1 PROCESS FOR PRODUCING NANOPARTICLES LADEN WITH ACTIVE INGREDIENT MERCK PATENT GMBH (DE) 2015-02-19 US disclosed