SCHEMBL4420162

SCHEMBL4420162

C=C(C(=O)O)C(C)C(O)CO

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
OR51E2 Q9H255 1/20 0.33
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
TP53 P04637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TGFBR1 P36897 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16468643 0.82 TSHR (0.33) TET2TET3TET1TP53
SCHEMBL11396886 0.78 LMNA (0.48) LMNAPDE4AUSP2SLCO1B1TDP1
SCHEMBL15129802 0.76 LMNA (0.41) LMNAPDE4AUSP2SLCO1B1TDP1
SCHEMBL1869406 0.75
SCHEMBL1869405 0.75
SCHEMBL4278295 0.74 LMNA (0.36) LMNAPDE4AUSP2SLCO1B1OR51E2
SCHEMBL13177001 0.74 FFAR3 (0.31) TET2TET3TET1
E968 SCHEMBL7107678 0.73 TGFBR1 (0.43) LMNAPDE4AUSP2SLCO1B1TDP1
E968 SCHEMBL960729 0.73 TGFBR1 (0.43) LMNAPDE4AUSP2SLCO1B1TDP1
E968 SCHEMBL2152820 0.73 TGFBR1 (0.43) LMNAPDE4AUSP2SLCO1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187701-B2 Porous humidity-control tile and method for manufacturing the same KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2012-05-29 US claimed
US-20090280313-A1 POROUS HUMIDITY-CONTROL TILE AND METHOD FOR MANUFACTURING THE SAME KOREA INSTITUTE OF MATERIALS SCIENCE (KR) 2009-11-12 US claimed
WO-2015093614-A1 COSMETIC COMPOSITION L'OREAL (FR) 2015-06-25 WO disclosed
US-8187701-B2 Porous humidity-control tile and method for manufacturing the same KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2012-05-29 US disclosed
US-20090280313-A1 POROUS HUMIDITY-CONTROL TILE AND METHOD FOR MANUFACTURING THE SAME KOREA INSTITUTE OF MATERIALS SCIENCE (KR) 2009-11-12 US disclosed