SCHEMBL16468664

SCHEMBL16468664

NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(=O)NC[C]=O

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 8/20 0.52
NPY1R P25929 6/20 0.52
NPY2R P49146 5/20 0.52
NPY5R Q15761 4/20 0.52
CHRND Q07001 5/20 0.47
CHRNA1 P02708 1/20 0.47
CHRNG P07510 1/20 0.47
CHRNB1 P11230 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23362899 0.88 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5R
SCHEMBL23362903 0.88 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30183642 0.86 NPY4R (0.58) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31619564 0.86 NPY4R (0.57) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30445400 0.85 NPY4R (0.53) NPY4RNPY1RNPY2R
SCHEMBL30367620 0.84 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30183809 0.84 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30882680 0.84 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30368454 0.84 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5R
SCHEMBL23362939 0.84 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9173951-B2 Carbohydrate-based drug delivery polymers and conjugates thereof NEKTAR THERAPEUTICS (US) 2015-11-03 US disclosed
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF NEKTAR THERAPEUTICS (US) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF STT3B, STT3A, DDOST NPY4R 2480/4885NPY1R 3329/4885NPY2R 3255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.