⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051721 | 0.85 | MEN1 (0.72) | — | |
| SCHEMBL793606 | 0.81 | — | — | |
| SCHEMBL3044354 | 0.79 | — | — | |
| SCHEMBL14474040 | 0.78 | ALDH1A1 (0.60) | — | |
| SCHEMBL8907984 | 0.77 | MEN1 (0.63) | — | |
| SCHEMBL9528369 | 0.76 | — | — | |
| SCHEMBL5067843 | 0.76 | — | — | |
| SCHEMBL2889862 | 0.76 | MAPT (0.61) | — | |
| SCHEMBL161830 | 0.76 | — | — | |
| SCHEMBL3541540 | 0.76 | KMT2A (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575309-A | A kind of preparation method of biological high molecular material | 左国幼 | 2019-04-05 | — | — | CN | claimed |
| EP-2918583-A1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | ELI LILLY AND CO. (US) | 2015-09-16 | — | — | EP | claimed |
| EP-2710000-B1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | LILLY CO ELI (US) | 2015-04-29 | — | — | EP | claimed |
| CN-104478850-A | Preparation method of derivatives of 2-aminothiophene-3 formamide | SHANGHAI INST TECHNOLOGY | 2015-04-01 | — | — | CN | claimed |
| US-20150072993-A1 | Parasiticidal Dihydroisoxazole Compounds | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2015-03-12 | — | — | US | claimed |
| EP-2710000-A1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | Eli Lilly and Company (US) | 2014-03-26 | — | — | EP | claimed |
| US-8648081-B2 | Parasiticidal dihydroisoxazole compounds | ELI LILLY AND COMPANY (US) | 2014-02-11 | — | — | US | claimed |
| US-20130217699-A1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2013-08-22 | — | — | US | claimed |
| WO-2012155352-A1 | DIHYDROISOXAZOLE COMPOUNDS, PARASITICIDAL USES AND FORMULATIONS THEREOF | ELI LILLY AND COMPANY (US) | 2012-11-22 | — | — | WO | claimed |
| WO-2012155676-A1 | PARASITICIDAL COMPOUNDS, METHODS, AND FORMULATIONS | ELI LILLY AND COMPANY (US) | 2012-11-22 | — | — | WO | claimed |
| WO-2012158396-A1 | PARASITICIDAL DIHYDROISOXAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2012-11-22 | — | — | WO | claimed |
| EP-0349239-B1 | Condensed pyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITH KLINE FRENCH LAB (GB) | 1994-03-16 | — | — | EP | claimed |
| EP-0349239-A2 | Condensed pyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-01-03 | — | — | EP | claimed |
| JP-8143571-A | — | — | None | — | — | JP | disclosed |
| US-20250296938-A1 | Compounds that Interact with the Ras Superfamily for the Treatment of Cancers, Inflammatory Diseases, Rasopathies, and Fibrotic Disease | SHY Therapeutics LLC (US) | 2025-09-25 | — | — | US | disclosed |
| US-12391705-B2 | Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease | SHY THERAPEUTICS, LLC (US) | 2025-08-19 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4111956-A | Process for the manufacture of heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |