⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476070 | 0.98 | KMT2A (0.65) | — | |
| Formamide SCHEMBL28359951 | 0.92 | KMT2A (0.59) | — | |
| Thiophene SCHEMBL19475667 | 0.90 | MEN1 (0.58) | — | |
| SCHEMBL27854840 | 0.83 | MEN1 (0.71) | — | |
| SCHEMBL164691 | 0.81 | — | — | |
| SCHEMBL3044354 | 0.79 | — | — | |
| SCHEMBL8907984 | 0.77 | MEN1 (0.63) | — | |
| SCHEMBL1424722 | 0.77 | ALDH1A1 (1.00) | — | |
| SCHEMBL26038517 | 0.76 | ALDH1A1 (0.61) | — | |
| SCHEMBL26205540 | 0.76 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053712-A | A kind of 2- aminothiophene -3- carboxylate methyl ester derivative C15H22N2O5The synthetic method of S | 南京大学连云港高新技术研究院 | 2018-12-21 | — | — | CN | claimed |
| EP-2346861-B1 | THIOPHENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-01-23 | — | — | EP | claimed |
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20060084805-A1 | Synthesis of thienopyridinone compounds and related intermediates | NANOSHIFT, LLC | 2006-04-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| CN-122055375-A | Compounds and methods for treating central nervous system disorders | 美国西北大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20260125356-A1 | TREATMENT OF LEISHMANIASIS | THE UNIV OF DURHAM (GB) | 2026-05-07 | — | — | US | disclosed |
| US-12421280-B2 | Insulin like growth factor binding protein bioactive peptide fragments | NORTHWESTERN UNIVERSITY (US) | 2025-09-23 | — | — | US | disclosed |
| EP-4605086-A1 | TREATMENT OF LEISHMANIASIS | The University of Durham (GB) | 2025-08-27 | — | — | EP | disclosed |
| WO-2025049670-A1 | COMPOUNDS AND METHODS FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | NORTHWESTERN UNIVERSITY (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-111936471-B | Non-fused thiophene derivatives and uses thereof | 埃尼奥制药公司 | 2024-10-29 | — | — | CN | disclosed |
| US-20240279236-A1 | COMPOUNDS AND METHODS OF TREATING TUBERCULOSIS | FIMBRION THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
| EP-0335979-A1 | THIENOPYRIMIDINE DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| CN-87100912-A | 3-(1-H-tetrazolium-5-yl) thieno-[2,3-d] pyrimidines-4 (3H)-ketone | — | 1987-12-23 | — | — | CN | disclosed |
| US-4701528-A | Intermediates useful in the preparation of 3,4-dihydro-4-oxothieno[2,3-d]pyrimidine-2-carboxylates and process for preparing same | BRISTOL-MYERS COMPANY (US) | 1987-10-20 | — | — | US | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4054656-A | ASTHMA, HAY FEVER, FOODS | MEAD JOHNSON & COMPANY (US) | 1977-10-18 | — | — | US | disclosed |