Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530738 | 0.75 | — | — | |
| SCHEMBL27725599 | 0.73 | TSHR (0.32) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1982478 | 0.73 | TSHR (0.39) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL8210522 | 0.72 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL28621880 | 0.72 | TSHR (0.41) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL9161010 | 0.71 | TSHR (0.40) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL466286 | 0.71 | TSHR (0.36) | TSHRMAPK1HSD17B10TDP1THRB | |
| Methylamine SCHEMBL28188491 | 0.70 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL3961385 | 0.70 | TSHR (0.38) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7623339 | 0.69 | TSHR (0.39) | TSHRMAPK1HSD17B10TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060383-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-11578093-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| EP-3030683-B1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2022-03-02 | — | — | EP | disclosed |
| US-20210147465-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-10800805-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10787573-B2 | Multimeric protected fluorescent reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190309171-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-10150872-B2 | Multimeric protected fluorescent reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-12-11 | — | — | US | disclosed |
| US-20180346507-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2018-12-06 | — | — | US | disclosed |
| US-9957291-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
| US-20180346507-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
| US-11578093-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
| US-12060383-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
| US-10800805-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
| US-20210147465-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | TSHR 3625/4885MAPK1 3932/4885HSD17B10 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.