SCHEMBL466286

SCHEMBL466286

O=C(O)C1=CC=CC(O)(C(=O)O)C1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3961385 0.79 TSHR (0.38) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL8210522 0.78 TSHR (0.37) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL8858302 0.78
SCHEMBL9161010 0.76 TSHR (0.40) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL31124103 0.76 KDM4E (0.30)
SCHEMBL8837708 0.76 TSHR (0.36) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1236079 0.74 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL544788 0.74 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL27361330 0.74 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1982478 0.74 TSHR (0.39) TSHRMAPK1HSD17B10TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114784346-B Proton exchange membrane for battery, preparation method and nanofiber composite structure 清华大学 2022-09-06 CN claimed
CN-114784346-A Proton exchange membrane for battery, preparation method and nanofiber composite structure 清华大学 2022-07-22 CN claimed
US-7452938-B2 Aqueous resin composition, aqueous coating material containing the composition, coating provided by the material, and metal plate coated with the material TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-11-18 US claimed
JP-59081192-A None JP disclosed
CN-122095316-A Composition for forming resist underlayer film 2026-05-26 CN disclosed
WO-2025095106-A1 RESIST UNDERLAYER FILM FORMATION COMPOSITION 日産化学株式会社 2025-05-08 WO disclosed
US-20250051352-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS ENI S.P.A. (IT) 2025-02-13 US disclosed
EP-4444723-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS ENI S.p.A. (IT) 2024-10-16 EP disclosed
CN-114746468-B Method for producing polymer 日产化学株式会社 2024-09-13 CN disclosed
CN-118284614-A Diaryloxybenzobisoxazole compounds disubstituted with thienothiophene groups 埃尼股份公司 2024-07-02 CN disclosed
US-20230321943-A1 Multilayered Container And Method For Producing Same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-12 US disclosed
EP-1120223-A1 Coinjection stretch blow molded container KURARAY CO., LTD. (JP) 2001-08-01 EP disclosed
US-6254669-B1 Bleed reduction agents for ink printing inks ZENECA LIMITED (GB) 2001-07-03 US disclosed
EP-0949056-A2 Coinjection stretch blow molded container KURARAY CO., LTD. (JP) 1999-10-13 EP disclosed
US-5686553-A TEREPHTHALIC ACID AND ETHYLENE GLYCOL COMONOMERS; MOLDABILITY KURARAY CO., LTD. (JP) 1997-11-11 US disclosed
EP-0774477-A2 Copolyesters and molded articles comprising the same KURARAY CO., LTD. (JP) 1997-05-21 EP disclosed
US-5298652-A N-substituted glycines, inhibitors of phospholipase A2 HOFFMANN-LA ROCHE INC. (US) 1994-03-29 US disclosed
JP-S5981192-A RECORDING MATERIAL TAOKA CHEM CO LTD 1984-05-10 JP disclosed
US-4138589-A CHEMICAL INTERMEDIATES FOR COMPOUNDS USED AS X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1979-02-06 US disclosed
US-4069250-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051352-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS SLC9A5, SLC7A5, SLC39A3 TSHR 400/4885MAPK1 2073/4885HSD17B10 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.