SCHEMBL8210522

SCHEMBL8210522

O=C(O)C1=CC=CC(C(=O)O)(C(=O)O)C1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466286 0.78 TSHR (0.36) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL3961385 0.77 TSHR (0.38) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL26103710 0.76 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1982478 0.76 TSHR (0.39) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL27420794 0.76 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL544788 0.76 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1236079 0.76 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL27361330 0.76 TSHR (0.35) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL28621880 0.75 TSHR (0.41) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL28623336 0.75 TSHR (0.37) TSHRMAPK1HSD17B10TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020085183-A1 SUBSTRATE LAYERED BODY MANUFACTURING METHOD AND LAYERED BODY 三井化学株式会社 2020-04-30 WO disclosed
EP-0992859-A2 Toner for developing latent eletrostatic images, binder resin for use in the toner, and image formation method using the toner Ricoh Company, Ltd. (JP) 2000-04-12 EP disclosed