Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725116 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4134518 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL335942 | 0.88 | CNR2 (0.50) | ALDH1A1LMNASMN1; SMN2FBP1CNR2 | |
| SCHEMBL29033283 | 0.88 | CNR2 (0.50) | ALDH1A1LMNASMN1; SMN2FBP1CNR2 | |
| SCHEMBL335941 | 0.88 | CNR2 (0.50) | ALDH1A1LMNASMN1; SMN2FBP1CNR2 | |
| Isophthalic Dicarboxaldehyde SCHEMBL4952540 | 0.83 | ALDH1A1 (0.67) | ALDH1A1UNGCYP2A6BRD4FBP1 | |
| Isophthalic Dicarboxaldehyde SCHEMBL180566 | 0.83 | ALDH1A1 (0.67) | ALDH1A1UNGCYP2A6BRD4FBP1 | |
| SCHEMBL28005548 | 0.81 | CNR2 (0.45) | ALDH1A1LMNASMN1; SMN2FBP1CNR2 | |
| SCHEMBL17472702 | 0.81 | TRIM24 (0.51) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL17472701 | 0.81 | TRIM24 (0.51) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963009-B1 | TRIARYLAMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC (JP) | 2017-11-01 | — | — | EP | disclosed |
| US-9436105-B2 | Triarylamine derivative and electrophotographic photosensitive member | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2016-09-06 | — | — | US | disclosed |
| EP-2963009-A1 | TRIARYLAMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | Kyocera Document Solutions Inc. (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-20150378268-A1 | TRIARYLAMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2358730-A1 | HIGH-PURITY REBAUDIOSIDE D AND APPLICATIONS | Purecircle SDN BHD (MY) | 2011-08-24 | — | — | EP | disclosed |
| WO-2011046423-A1 | HIGH-PURITY REBAUDIOSIDE D AND APPLICATIONS | PURECIRCLE SDN BHD (MY) | 2011-04-21 | — | — | WO | disclosed |
| CN-1245381-C | Phenylglycine derivatives | HOFFMANN LA ROCHE (CH) | 2006-03-15 | — | — | CN | disclosed |
| CN-1334798-A | Phenylglycine derivatives | HOFFMANN LA ROCHE (CH) | 2002-02-06 | — | — | CN | disclosed |
| EP-0219308-A2 | 2-Substituted quinolines | MERCK FROSST CANADA INC. (CA) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150378268-A1 | TRIARYLAMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | NAT1, TYR, PAH | ALDH1A1 159/4885MAPT 3623/4885LMNA 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.