Sugi Predict

Sugi Predict / Compounds / SCHEMBL4134518

SCHEMBL4134518

SCHEMBL4134518

C/C=C/c1cccc(C=O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.50
▸ MAPT P10636 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.46
▸ UNG P13051 1/20 0.45
▸ CYP2A6 P11509 1/20 0.44
▸ BRD4 O60885 1/20 0.42
▸ FBP1 P09467 1/20 0.42
▸ CNR2 P34972 1/20 0.42
▸ MAOA P21397 3/20 0.41
▸ MAOB P27338 3/20 0.41
▸ HPGD P15428 1/20 0.41
▸ SRC P12931 1/20 0.40
▸ CCNB2 O95067 1/20 0.39
▸ CDK1 P06493 1/20 0.39
▸ CDK4 P11802 1/20 0.39
▸ CCNB1 P14635 1/20 0.39
▸ CCND1 P24385 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20725116 1.00 ALDH1A1 (0.50) ALDH1A1MAPTLMNAHTTSMN1; SMN2
SCHEMBL1647162 1.00 ALDH1A1 (0.50) ALDH1A1MAPTLMNAHTTSMN1; SMN2
SCHEMBL335942 0.88 CNR2 (0.50) ALDH1A1LMNASMN1; SMN2FBP1CNR2
SCHEMBL29033283 0.88 CNR2 (0.50) ALDH1A1LMNASMN1; SMN2FBP1CNR2
SCHEMBL335941 0.88 CNR2 (0.50) ALDH1A1LMNASMN1; SMN2FBP1CNR2
Isophthalic Dicarboxaldehyde SCHEMBL4952540 0.83 ALDH1A1 (0.67) ALDH1A1UNGCYP2A6BRD4FBP1
Isophthalic Dicarboxaldehyde SCHEMBL180566 0.83 ALDH1A1 (0.67) ALDH1A1UNGCYP2A6BRD4FBP1
SCHEMBL28005548 0.81 CNR2 (0.45) ALDH1A1LMNASMN1; SMN2FBP1CNR2
SCHEMBL17472702 0.81 TRIM24 (0.51) ALDH1A1MAPTLMNAHTTSMN1; SMN2
SCHEMBL17472701 0.81 TRIM24 (0.51) ALDH1A1MAPTLMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090068126-A1 Composition for surface photoprotection SOARES ROMEIRO LUIZ ANTONIO 2009-03-12 — — US claimed
CN-101111475-A Antiviral compounds and methods BIOTRON LTD (AU) 2008-01-23 — — CN claimed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 — — EP claimed
CN-110268324-B Blue photosensitive resin composition, color filter manufactured using the same, and image display device 东友精细化工有限公司 2023-05-16 — — CN disclosed
CN-110419002-B Photosensitive resin composition, color filter prepared using the same, and image display device 东友精细化工有限公司 2023-02-21 — — CN disclosed
CN-109844640-B Self-emission type photosensitive resin composition, color filter and image display device manufactured using the same 东友精细化工有限公司 2022-06-28 — — CN disclosed
WO-2020257622-A1 GNIDIMACRIN DERIVATIVES AS POTENT HIV-1 INHIBITORS AND LATENCY REVERSING AGENTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2020-12-24 — — WO disclosed
CN-110419002-A Photosensitive resin composition, color filter prepared using the same, and image display device DONGWOO FINE CHEM CO LTD 2019-11-05 — — CN disclosed
CN-110396034-A A kind of preparation method of allyl compound SHANGHAI INST TECH 2019-11-01 — — CN disclosed
CN-109922802-A triazole benzamide derivatives and related compositions and methods of treatment AN2H探索有限公司 2019-06-21 — — CN disclosed
CN-109844640-A Self-emission type photosensitive resin composition, color filter and image display device manufactured using the same 东友精细化工有限公司 2019-06-04 — — CN disclosed
CN-101111475-B Antiviral compounds and methods BIOTRON LTD 2012-09-05 — — CN disclosed
CN-102089262-A Derivatives of 3- (2-hydroxy-5-methylphenyl) -N, N-diisopropyl-3-amphetamine and methods of use thereof CONCERT PHARMACEUTICALS INC 2011-06-08 — — CN disclosed
US-7649015-B2 Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds GILEAD SCIENCES, INC. (US) 2010-01-19 — — US disclosed
US-20090068126-A1 Composition for surface photoprotection SOARES ROMEIRO LUIZ ANTONIO 2009-03-12 — — US disclosed
CN-100386322-C Synthesis method of flavonoid compound capram pyrane UNIV BOHAI (CN) 2008-05-07 — — CN disclosed
CN-101111475-A Antiviral compounds and methods BIOTRON LTD (AU) 2008-01-23 — — CN disclosed
CN-1718576-A Synthesis method of flavonoid compound capram pyrane UNIV BOHAI (CN) 2006-01-11 — — CN disclosed
CN-1673219-A Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them ISK AMERICAS INC (US) 2005-09-28 — — CN disclosed
US-3954981-A Triazolocycloalkylhydrothiadiazine derivatives RICHARDSON-MERRELL INC. (US) 1976-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068126-A1 Composition for surface photoprotection S100A10, CD63, S100A9 ALDH1A1 1804/4885MAPT 719/4885LMNA 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.