Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823120 | 0.86 | TRPV1 (0.41) | TRPV1HTTHSD17B10TDP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3824636 | 0.85 | TRPV1 (0.40) | TRPV1HTTHSD17B10TDP1CYP3A4 | |
| SCHEMBL14093265 | 0.83 | TRPV1 (0.43) | TRPV1HTTHSD17B10CYP3A4PORCN | |
| Hydrochloric Acid SCHEMBL3823968 | 0.82 | TRPV1 (0.42) | TRPV1HTTHSD17B10CYP3A4PORCN | |
| SCHEMBL1781583 | 0.79 | RAB9A (0.47) | TRPV1HTTHSD17B10CYP3A4MEN1 | |
| SCHEMBL3826237 | 0.77 | CYP3A4 (0.53) | TRPV1HSD17B10TDP1CYP3A4ADORA2A | |
| SCHEMBL987860 | 0.75 | TRPV1 (0.45) | TRPV1HTTHSD17B10MEN1KMT2A | |
| SCHEMBL1781223 | 0.75 | RAB9A (0.47) | TRPV1HTTHSD17B10TDP1CYP3A4 | |
| SCHEMBL3828968 | 0.75 | TRPV1 (0.45) | TRPV1HTTHSD17B10CYP3A4 | |
| SCHEMBL3829813 | 0.75 | TRPV1 (0.44) | TRPV1HTTHSD17B10CYP3A4PORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086326-B1 | CYCLOHEXENYL-ARYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2014-01-08 | — | — | EP | disclosed |